Women's Health Weekly
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Breast Cancer
Deregulation of X-linked genes may promote mammary gland tumorigenesis
November 24th, 2005
Deregulation of X-linked genes may create genetic instability, thereby promoting mammary gland tumorigenesis. "While contribution of X chromosome in the susceptibility of prostate and ovarian cancer has been demonstrated, the role of X-linked genes in breast cancinogenesis is not clearly known. This study investigated and compared the X-linked gene expression profiles of MMTV-c-myc transgenic mammary tumor (MT) or MMTV-c-myc/MT-tgf-alpha double transgenic mouse mammary tumor (DT) to lactating mammary gland," scientists writing in the journal Breast Cancer Research and Treatment report. A. Thakur and colleagues at Wayne State University found...
Source: Women's Health Weekly (2005-11-24)
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