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Surgery

Routine use of axillary dissection not recommended for ITC-positive sentinel node metastases

Published in Women's Health Weekly, December 1st, 2005

The routine use of axillary dissection (ALND) was not recommended for isolated tumor cells (ITC)-positive sentinel node (SLN) metastases.

"Controversy exists regarding ALND for SLN metastases detected as ITC. We hypothesized that the number of positive non-SLNs is low and ALND is unnecessary for most patients with ITC. From 1995 to 1999, 634 breast cancer patients underwent SLND," investigators in the United States reported.

"SLNs were examined using immunohistochemistry if hematoxylin and eosin was negative. ALND was recommended for ITC-positive SLNs. Seventy-eight patients (12.3%) with ITC-positive SLNs were offered ALND. Sixty-one consented,...

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