Women's Health Weekly
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Breast Cancer Treatment
Extracapsular spread does not identify patients benefited by radiotherapy
December 1st, 2005
Extracapsular spread does not provide prognostic value to identify patients who would be benefited by radiotherapy. Researchers in Switzerland "sought to determine retrospectively whether extracapsular spread (ECS) might identify a subgroup that could benefit from radiotherapy after mastectomy, especially patients with 1 to 3 positive lymph nodes (LN1-3+). "We randomized 1,475 premenopausal women with node-positive breast cancer to three, six, or nine courses of "classical" CMF (cyclophosphamide, methotrexate, and fluorouracil), noted G. Gruber and colleagues. "After a review of all pathology forms, 933 patients (63%) had information on the presence...
Source: Women's Health Weekly (2005-12-01)
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