Women's Health Weekly
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Breast Cancer
Genetic patterns in breast cancer lymph node metastases are heterogeneous
December 8th, 2005
Genetic patterns in breast cancer lymph node metastases are heterogeneous. According to recent research from the Netherlands, "the axillary lymph node status is the most powerful prognostic factor for breast cancer patients to date. The molecular mechanisms that control lymph node metastasis, however, remain poorly understood." "To define patterns of genes or gene regulatory pathways that drive breast cancer lymph node metastasis, we compared the gene expression profiles of 15 primary breast carcinomas and their matching lymph node metastases using microarrays. In general, primary breast carcinomas and lymph node metastases do not differ at the...
Source: Women's Health Weekly (2005-12-08)
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