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Women's Health Weekly

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Gynecology



Thrombospondin-1 levels rise in invasive vulvar squamous cell carcinoma



December 8th, 2005

Thrombospondin-1 (TSP-1) levels rise in invasive vulvar squamous cell carcinoma.

According to recent research from Austria, "TSP-1 is a multifunctional matricellular glycoprotein involved in several mechanisms critical to the formation and progression of solid tumors including cell adhesion, proliferation, migration, invasion, and angiogenesis. The present study was designed to investigate the expression of TSP-1 in invasive vulvar squamous cell carcinoma."

"A total of 75 invasive vulvar squamous cell carcinomas were evaluated for TSP-1 expression by immunohistochemistry. Results were correlated with the clinicopathologic parameters including tumor...


Source: Women's Health Weekly (2005-12-08)

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