Women's Health Weekly
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Breast Cancer
Breast cancer cells are prone to apoptosis and growth arrest after protein silencing
December 15th, 2005
According to recent research from the People's Republic of China, silencing of human phosphatidylethanolamine-binding protein 4 (hPEBP4) sensitizes breast cancer cells to tumor necrosis factor-alpha-induced apoptosis and cell growth arrest. "The current therapeutic approach is not so effective in breast cancer patients. Alternative treatment protocols aimed at different targets need to be explored." "We recently reported a novel phosphatidylethanolamine-binding protein, hPEBP4, as an antiapoptotic molecule. The finding led us to explore a promising approach for breast cancer therapy via silencing the expression of hPEBP4," wrote X.J. Wang and...
Source: Women's Health Weekly (2005-12-15)
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