Women's Health Weekly
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Breast Cancer Risk Factors
Breast cancer risk is not seen with certain estrogen metabolizing polymorphisms
December 15th, 2005
A role in breast cancer risk was not seen with certain estrogen metabolizing polymorphisms in older white women. Scientists in the United States conducted a study "to investigate breast cancer risk according to metabolizing genes polymorphisms in older women." F. Modugno and colleagues explained, "A subset (43.8%) of 4248 older, white women from the Study of Osteoporotic Fractures (SOF) were genotyped for the catechol-O-methyltransferase (COMT) Val108Met polymorphism and the CYP1A1* 2C locus. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the associations...
Source: Women's Health Weekly (2005-12-15)
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