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Cancer Risk Factors

Manipulating elevated LH levels in BRCA1 mutation carriers may reduce cancer risk

Published in Women's Health Weekly, December 15th, 2005

The findings of a small study led researchers to speculate whether the manipulation of elevated LH levels in BRCA1 mutation carriers may reduce cancer risk.

"BRCA1 mutation carriers have up to 80% life-time risk of developing breast cancer and 20-40% risk of developing ovarian cancer. High LH levels have been linked to increased risks of both breast and ovarian cancers in some studies and it is unknown whether gonadotropin levels are associated with BRCA1 mutation status," stated scientists from Switzerland.

"The aim of [our] study," wrote H. Jernstrom and colleagues, "was to explore whether gonadotropin levels were associated with...

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