Women's Health Weekly
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Cervical Cancer
Laminin-5 gamma 2 chain expression aids identification of invasive cervical lesions
December 15th, 2005
Laminin-5 gamma 2 chain expression aids in the identification of invasive and microinasive cervical lesions. Scientists in Belgium conducted a study "to analyze the expression of laminin-5 gamma 2 chain, a protein which plays a major role in keratinocyte migration, in cervical intraepithelial neoplasia (CIN), and invasive cervical carcinoma associated with high-risk oncogenic human papillomaviruses (HR-HPVs)." "The expression of laminin-5 gamma 2 chain protein has been analyzed by immunohistochemistry in 17 cases of low-grade squamous intraepithelial lesions (LSIL-CIN1), 35 high-grade squamous intraepithelial lesions (HSIL-CIN2/3), 18 microinvasive...
Source: Women's Health Weekly (2005-12-15)
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