Women's Health Weekly
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Breast Cancer
CHEK2*1100delC allele imparts high risk for familial breast cancer
December 22nd, 2005
The CHEK2*1100delC allele imparts high risk for familial breast cancer and may offer prognostic value. "The allele CHEK2*1100delC doubles the risk of breast cancer in unselected women, but could a greater risk in women with a family history of the disease, particularly of bilateral breast cancer." The aim of a study by scientists in England was "to measure the risk of breast cancer in relatives of women with bilateral breast cancer who were carriers of this allele." N. Johnson and colleagues explained, "A population-based series of 469 bilateral breast cancer cases ascertained through English cancer registries were genotyped for...
Source: Women's Health Weekly (2005-12-22)
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