Women's Health Weekly
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Cancer Risk Factors
Estradiol and progesterone levels have no effect on micronucleus assay variability
December 22nd, 2005
Estradiol and progesterone levels have no effect on micronucleus assay variability. According to researchers in Belgium, "To investigate chromosomal radiosensitivity of lymphocytes, the micronucleus (MN) assay has been used for many years. The results of these studies suggest the use of the MN assay as a biomarker for cancer predisposition." "However," stated A. Baeyens and colleagues, "the MN assay has still some limitations associated with the reproducibility and sensitivity. Especially a high intra-individual variability has been observed. An explanation for this high intra-individual variability is not yet available." The...
Source: Women's Health Weekly (2005-12-22)
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