Women's Health Weekly
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Cervical Cancer
Interaction of host and viral risk factors required for development of cervical carcinoma
December 22nd, 2005
An interaction of host and viral risk factors seem to be required for the development of cervical carcinoma. According to recent research from Sweden, "Infection by oncogenic human papillomavirus (HPV) is a necessary but not sufficient cause of cervical carcinoma. Several host genetic and viral factors have been reported to increase the risk of carcinoma development given an HPV infection." "In our study, we have analyzed the contribution of HPV 16 E6 sequence subtype and allelic variation at human leukocyte antigen (HLA) class II loci to the risk of developing cervical carcinoma in situ. Non-European-like HPV 16 E6 sequence subtypes were not found...
Source: Women's Health Weekly (2005-12-22)
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