Women's Health Weekly
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Apoptosis
Gleditsia sinensis fruit extract induced apoptosis in human carcinoma cells
December 22nd, 2005
Researchers indicated that Gleditsia sinensis (GSE) fruit extract induced apoptosis in human carcinoma cells. "The anomalous fruit extract of GSE was shown to possess anticancer potential on various solid tumor and leukemia cell lines in vitro. We have recently demonstrated that the mitochondrial-dependent apoptotic pathway including mitochondrial membrane potential depolarization, changes in the level of reactive oxygen species and activation of caspase 3 were recruited in GSE-induced apoptosis," scientists in the People's Republic of China reported. "Whether receptor-dependent APO-1/Fas apoptotic pathway is also involved remains uncertain....
Source: Women's Health Weekly (2005-12-22)
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