Women's Health Weekly
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Breast Cancer
HLA-B7 allele associated with susceptibility to breast cancer in Spanish women
January 5th, 2006
The HLA-B7 allele was associated with susceptibility to breast cancer in Spanish women. According to a study from Spain, "Several HLA alleles are associated with susceptibility or protection in breast cancer. The particular allele varies depending on the geographical region." "A study in a small group of Spanish patients using serological methods found an association with HLA-B7. We undertook a larger study in southern Spain using molecular biology techniques. Genotype variants of HLA class I and II were typed by PCR-SSP in 132 breast cancer patients and 382 healthy controls. The frequency of the HLA-B7 allele was increased in the patients compared...
Source: Women's Health Weekly (2006-01-05)
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