Women's Health Weekly
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Cardiovascular Disease
Hypertension and estrogen receptor polymorphisms are linked to LV hypertrophy
January 5th, 2006
Hypertension and estrogen receptor polymorphisms are linked to left ventricular hypertrophy. "Left ventricular (LV) hypertrophy is a significant risk factor for cardiovascular disease. Given sex-based differences in cardiac structure and remodeling." Investigators in the United States "hypothesized that variation in estrogen pathway genes might be associated with alteration of LV structure." I. Peter and colleagues described their research: "We studied 1,249 unrelated individuals, 547 men and 702 women (mean age 59 years) from the Framingham Heart Study. Eight single nucleotide polymorphisms in the genes for estrogen receptor alpha and estrogen...
Source: Women's Health Weekly (2006-01-05)
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