Cervical Cancer Screening
Using higher cutoff reduces sensitivity of Hybrid Capture II assay
Published in Women's Health Weekly, January 5th, 2006
According to researchers in Spain, "The aim of [our] study was to evaluate whether the results of the Hybrid Capture II (HCII) assay for detecting high-grade squamous intraepithelial lesions (H-SIL) or cervical carcinoma can be improved by increasing the relative light units (RLU) level."
J. Ordi and colleagues explained, "We included 2,271 women (mean age 38.7 ±12.3, range 15-92) referred to a colposcopic clinic due to cytology of atypical cells of unknown significance, SIL or carcinoma. All women...
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