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Women's Health Weekly

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Adverse Drug Reaction



Octyl-methoxycinnamate in sunscreen has estrogenic and nonestrogenic toxicity



January 5th, 2006

Octyl-methoxycinnamate (OMC) in sunscreen has estrogenic and nonestrogenic toxic effects.

"Sun protection products contain a variety of UV filters," including OMC, toxicologists in Germany explained. "Recently, an uterotrophic effect in immature rats has been reported, indicating that OMC might have estrogenic properties and thus is an endocrine active chemical (EAC)."

"However, determination of an estrogenic activity in the uterus only is a restricted approach with the potential risk of missing undesirable actions in other organs regulated by estrogens," argued H. Klammer and colleagues at the University of Gottingen. In their study, a...


Source: Women's Health Weekly (2006-01-05)

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