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Women's Health Weekly

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Breast Cancer



Conjugated linoleic acid may limit VEGF-A expression in breast tumors



January 12th, 2006

Conjugated linoleic acid (CLA) may limit VEGF-A (vascular endothelial growth factor A) expression in breast tumors.

"CLA, a naturally occurring compound found in ruminant dairy and beef products, has been shown to possess anticancer ability in vivo and in vitro. There are several CLA isomers in ruminant produced food products, among which t10,c12-CLA and c9,t11-CLA are most potent," investigators in the United States report.

L.S. Wang and colleagues, Ohio State University said, "VEGF-A has been implicated as an angiogenesis-activating cytokine. Our previous results indicated that CLA induced suppression of VEGF-A in MCF-7 cells, which may be one of...


Source: Women's Health Weekly (2006-01-12)

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