Cancer Gene Therapy
Akt blocks breast cancer cell motility and invasion
Published in Women's Health Weekly, January 19th, 2006
"The phosphoinositide 3-kinase (PI 3-K) signaling axis is intimately associated with deregulated cancer cell growth, primarily by promoting increased survival through Akt/PKB (protein kinase B). However, there is relatively little information on the role of Akt in cancer cell motility, a key phenotype of invasive carcinomas."
"Here," wrote M. Yoelilerner and colleagues, Harvard University, "we report that activation of Akt...
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