Women's Health Weekly
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Breast Cancer
CD24 expression was associated with tumor growth and metastasis
February 2nd, 2006
CD24 expression was associated with tumor growth and metastasis. According to recent research from Germany, "The glycosylphosphatidylinositol-anchored membrane protein CD24 functions as an adhesion molecule for P-selectin and L1 and plays a role in B-cell development and neurogenesis. Over the last few years, a large body of literature has also implicated CD24 expression in tumorigenesis and progression." "Here, we show that ectopic CD24 expression can be sufficient to promote tumor metastasis in experimental animals. By developing a doxycycline-inducible system for the expression of CD24 in breast cancer cells, we have also analyzed the cellular...
Source: Women's Health Weekly (2006-02-02)
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