Women's Health Weekly
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Breast Cancer
Researchers describe findings in breast cancer studies
February 2nd, 2006
Breast cancer research advances have been reported from the United States and Japan. Study 1: Mice lacking cyclooxygenase-2 (Cox-2) capacity have reduced mammary tumorigenesis and angiogenesis. "The inducible prostaglandin synthase Cox-2 is overexpressed in approximately 40% of human breast cancers and at higher frequencies in preinvasive ductal carcinoma in situ (DCIS). Cox-2 expression is particularly associated with overexpression of human epidermal growth factor receptor 2 (HER2/neu)," investigators in the United States report. "To definitively interrogate the role of Cox-2 in mammary neoplasia, we have used a genetic...
Source: Women's Health Weekly (2006-02-02)
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