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Women's Health Weekly

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Breast Cancer



Outcome after preoperative chemotherapy for breast cancer predicted by nomogram



February 9th, 2006

Nomograms were developed that could predict pathologic outcome after preoperative chemotherapy (PC) for breast cancer.

In a recently published article, investigators in the United States detailed a study conducted "to combine clinical variables associated with pathologic complete response (pCR) and distant metastasis-free survival (DMFS) after PC into a prediction nomogram. Data from 496 patients treated with anthracycline PC at the Institut Gustave Roussy were used to develop and calibrate a nomogram for pCR based on multivariate logistic regression. This nomogram was tested on two independent cohorts of patients treated at the M.D. Anderson Cancer Center."

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Source: Women's Health Weekly (2006-02-09)

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