Women's Health Weekly
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Breast Cancer
Polymorphisms of DNA mismatch repair gene hMSH2 linked to breast cancer risk
February 9th, 2006
Polymorphisms of the DNA mismatch repair (MMR) gene hMSH2 was linked to carcinogenesis of the breast. According to recent research from Poland, "The response of the cell to DNA damage and its ability to maintain genomic stability by DNA repair are crucial in preventing cancer initiation and progression. Therefore, polymorphism of DNA repair genes may affect the process of carcinogenesis." "The importance of genetic variability of the components of MMR genes is well documented in colorectal cancer, but little is known about its role in breast cancer. hMSH2 is one of the crucial proteins of MMR. We performed a case-control study to test the association...
Source: Women's Health Weekly (2006-02-09)
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