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Women's Health Weekly

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Antifungal Therapy



Fluconazole resistance by Candida isolates is linked to increased expression of CDR1



February 23rd, 2006

Fluconazole resistance by Candida isolates is linked to increased expression of CDR1.

Researchers at the Universidade Federal do Espirito Santo in Brazil report, "We conducted a study to determine the antifungal susceptibility of vaginal Candida isolates from HIV-infected Brazilian women. Among 127 women enrolled, positive cultures for yeast were obtained from 31 of 38 (81%) women with symptomatic vulvovaginitis, and from 41 of 89 (46%) asymptomatic women."

"Susceptibility testing demonstrated 11 of the 72 isolates had either resistance or dose-dependent susceptibility to azole drugs, including four Candida albicans strains," noted M.A....


Source: Women's Health Weekly (2006-02-23)

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