Women's Health Weekly
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Breast Cancer
Single-gene biomarker identifies breast cancers
February 23rd, 2006
According to recent research from the United States, a single-gene biomarker identifies breast cancers associated with immature cell type and short duration of prior breastfeeding. "The pathogenesis of breast cancers that do not express estrogen receptors or Her-2/neu receptors (ER-/HER2-phenotype) is incompletely understood," wrote W.F. Symmans and colleagues, M.D. Anderson Cancer Center. "We had observed markedly elevated gene expression of gamma-aminobutyric acid type A (GABA(A)) receptor subunit pi (GABA pi, GABRP) in some breast cancers with ER-/HER2-phenotype. In this study, transcriptional profiles (TxPs) were obtained from 82 primary invasive...
Source: Women's Health Weekly (2006-02-23)
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