Women's Health Weekly
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Breast Cancer
The ATM gene is linked to infiltrating breast carcinoma angiogenesis and infiltration
February 23rd, 2006
The ATM gene is linked to infiltrating breast carcinoma angiogenesis and infiltration. "The product of the ATM gene, mutated in the human genetic disorder ataxia-telangiectasia (A-T) plays a key role in the detection and repair of DNA double-strand breaks. A-T is defined by progressive cerebellar ataxia, telangiectasia, sensitivity to ionizing radiation, and genomic instability with cancer predisposition," scientists in Spain report. "On the other hand, increased angiogenesis is essential for tumor growth and metastasis. The aim of this study was to investigate ATM expression in breast carcinomas and its relationship to neoangiogenesis. Fifty-two...
Source: Women's Health Weekly (2006-02-23)
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