Women's Health Weekly
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Cancer Gene Therapy
Adenovirus vectors transcriptionally target breast cancer
February 23rd, 2006
Recent research from the United States published in the journal Molecular Cancer Therapeutics has detailed transcriptional targeting modalities in breast cancer gene therapy using adenovirus vectors controlled by alpha-lactalbumin promoter. "The breast-specific antigen alpha-lactalbumin is expressed in >60% of breast cancer tissues. To evaluate the effect of gene therapy for breast cancer by controlling adenovirus replication with human alpha-lactalbumin promoter, we investigated the activity of a 762-bP human alpha-lactalbumin promoter," wrote X. Li and colleagues, Indiana University. "alpha-lactalbumin promoter showed significantly higher...
Source: Women's Health Weekly (2006-02-23)
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