Women's Health Weekly
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Cancer Risk Factors
Breast and uterine cancer risk are associated with increased chromosomal instability
February 23rd, 2006
Breast and uterine cancer risk are associated with increased chromosomal instability. According to recent research from Japan, "The DNA double-strand breaks (DSBs) repair pathway has been implicated in maintaining genomic integrity via suppression of chromosomal rearrangements. DNA-dependent protein kinase (DNA-PK) has an important role with DNA DSBs repair." "In this study, 93 of untreated cancer patients and 41 of cancer-free healthy volunteers were enrolled," reported M. Someya and colleagues of Sapporo Medical University. "Peripheral blood was collected, separated and centrifuged; DNA-PK activity was measured by DNA-pull-down assay. The...
Source: Women's Health Weekly (2006-02-23)
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