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Endocrinology

Newly discovered brain hormone puts brakes on reproduction

Published in Women's Health Weekly, March 2nd, 2006

University of California, Berkeley, researchers have discovered a new brain hormone that inhibits the action of the mammalian reproductive system.

The hormone, a small protein, or peptide, called gonadotropin-inhibitory hormone (GnIH), puts the brakes on reproduction by directly inhibiting the action of the central hormone of the reproductive system: gonadotropin releasing hormone (GnRH). GnRH stimulates the pituitary gland to activate the reproductive system, whereas GnIH appears to reduce the effects of GnRH stimulation.

Researchers have long sought inhibitors of pituitary gonadotropins, but many had come to believe that such a direct inhibitor was...

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