Women's Health Weekly
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Breast Cancer
KiSS-1 expression is increased in human breast cancer
March 2nd, 2006
KiSS-1 expression was increased in human breast cancer. "The KiSS-1 gene encodes a 145 amino acid residue peptide that is further processed to a final peptide, metastin, a ligand to a G-coupled orphan receptor (OT7T175/AXOR12). KiSS-1 has been identified as a putative human metastasis suppressor gene in melanomas and in breast cancer cell lines," scientists writing in the journal Clinical & Experimental Metastasis reported. "This study aimed to determine the expression and distribution of KiSS-1 and its receptor in human breast cancer tissues and to identify a possible link between expression levels and patient prognosis. Frozen sections from...
Source: Women's Health Weekly (2006-03-02)
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