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Adverse Drug Reactions

Antidepressant use in pregnancy appears associated with neonatal withdrawal symptoms

Published in Women's Health Weekly, March 2nd, 2006

In a study from Israel, almost one-third of 60 newborn infants whose mothers took antidepressants during pregnancy experienced neonatal abstinence syndrome, a type of withdrawal with symptoms that include high-pitched crying, tremors, and disturbed sleep.

Between one-tenth and one-fourth of women will develop depression in their lifetimes, according to background information in the article. The stress of pregnancy can worsen the condition and increase the need for medications. Selective serotonin reuptake inhibitors (SSRIs) are a commonly used class of antidepressants; they are known to cross the placenta, however, prompting research into their effects on...

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