Women's Health Weekly
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Breast Cancer
A new I kappa B kinase beta inhibitor prevents human breast cancer progression
March 9th, 2006
A new I kappa B kinase beta inhibitor prevents human breast cancer progression through negative regulation of cell cycle transition. According to recent research from Japan, "Constitutive nuclear factor-kappa B (NF-kappa B) activity plays a crucial role in the development and progression of lymphoma, leukemia, and some epithelial cancers. Given the contribution of NF-kappa B in carcinogenesis, a novel approach that interferes with its activity might have therapeutic potential against cancers that respond poorly to conventional treatments." "Here, we have shown that a new I kappa B kinase beta inhibitor, IMD-0354, suppressed the growth of human breast...
Source: Women's Health Weekly (2006-03-09)
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