Women's Health Weekly
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Cancer Gene Therapy
Antisense-cisplatin combination treatment is potentially useful in breast cancer
March 9th, 2006
According to a study from the United States, BCL-2 antisense and cisplatin combination treatment of MCF-7 breast cancer cells with or without functional p53 is a potentially useful therapeutic strategy. "Chemotherapy has been used for treatment of breast cancer but with limited success. We characterized the effects of bcl-2 antisense and cisplatin combination therapy in two human isogenic breast carcinoma cells p53(+)MCF-7 and p53(-)MCF-7/E6," wrote H. Basma and colleagues, College of Medicine. "The transferrin-facilitated lipofection strategy we have developed yielded same transfection efficiency in both cells. Bcl-2 antisense delivered with this...
Source: Women's Health Weekly (2006-03-09)
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