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Coronary Artery Disease

Sibling history may identify heart disease risk in women despite low Framingham risk score

"The Framingham risk estimation (FRE) serves as the basis for identifying which asymptomatic adults should be treated with aspirin and lipid-lowering therapy in primary prevention. However, the FRE generally yields low estimates of 10-year 'hard' coronary heart disease (CHD) event risk with few women (<70 years) qualifying for preventive pharmacologic therapy despite relatively high lifetime risk," noted investigators at Johns Hopkins University.

E.D. Michos and colleagues stated, "We postulated that traditional risk factor assessment might fail...

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