Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Cancer Therapy
Antitumor benzothiazoles showed inhibitory activity against cancer cell lines
March 9th, 2006
Antitumor benzothiazoles showed inhibitory activity against lung, colon, and breast cancer cell lines. According to recent research from England, "A series of new 2-phenylbenzothiazoles has been synthesized on the basis of the discovery of the potent and selective in vitro antitumor properties of 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (8n; GW 610. NSC 721648)." "Synthesis of analogues substituted in the benzothiazole ring was achieved via the reaction of o-aminothiophenol disulfides with substituted benzaldehydes under reducing conditions. Compounds were evaluated in vitro in 4 human cancer cell lines, and compound 8n was found to possess...
Source: Women's Health Weekly (2006-03-09)
|
