Cancer Therapy
Irofulven cytotoxicity characterized in human cancer cells
Published in Women's Health Weekly, March 9th, 2006
"This study assessed the cytotoxic effects of irofulven in combination with oxaliplatin and cisplatin in a panel of human cancer cell lines. Growth inhibition studies were performed using the human HT29 colon cancer cell line, irofulven-resistant derivative HT29/IF2, breast cancer cell line MCF7, and ovarian cancer line CAOV3. Irofulven-oxaliplatin combinations were compared with irofulven-cisplatin combinations in the same cell lines using similar experimental settings," scientists writing in the journal Cancer Chemotherapy and...
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