Women's Health Weekly
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Breast Cancer
Related proteins regulated differently between normal and breast cancer cells
March 16th, 2006
Several functionally related proteins were differentially regulated between normal and breast cancer cell lines. According to recent research published in the Journal of Proteome Research, "Normal and cancer cell line proteomes were profiled using high throughput mass spectrometry techniques. Application of protein-level and peptide-level sample fractionation combined with LCMS/MS analysis enabled identification of 2235 unmodified proteins representing a broad range of functional and compartmental classes." "An iterative multistep search strategy was used to identify post-translational modifications, revealing several proteins that are...
Source: Women's Health Weekly (2006-03-16)
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