Women's Health Weekly
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Cancer Prognostics
Piwil2 expression used as cancer prognosticator
March 16th, 2006
Piwil2 expression could be used as a cancer prognosticator. "The genes of the piwi family are defined by conserved PAZ and Piwi domains and play important roles in stem-cell self-renewal, RNA silencing and translational regulation in various organisms. Both, mouse and human Piwil2 genes, members of the piwi gene family, are specifically expressed in testis," researchers in Germany reported. "We report here enhanced expression of the human Piwil2 gene in testicular seminomas, but not in testicular non-seminomatous tumors. Expression of the Piwil2 gene was also found in different tumors examined, including prostate, breast, gastrointestinal, ovarian...
Source: Women's Health Weekly (2006-03-16)
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