Women's Health Weekly
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Cancer Therapy
Antitumor activity of NGR-TNF in combination with chemotherapeutic drugs studied
March 16th, 2006
The antitumor activity of NGR-tumor necrosis factor (TNF) in combination with various chemotherapeutic drugs was studied. According to recent research published in the journal Clinical Cancer Research, "Subnanogram doses of NGR-TNF, a TNF-alpha derivative able to target tumor neovessels, can enhance the antitumor activity of doxorubicin and melphalan in murine models. We have examined the antitumor activity of NGR-TNF in combination with various chemotherapeutic drugs acting via different mechanisms, including, besides doxorubicin and melphalan, cisplatin, paclitaxel, and gemcitabine." "Chemotherapeutic drugs were tested alone and in...
Source: Women's Health Weekly (2006-03-16)
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