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Women's Health Weekly

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Breast Cancer



Breast cancer drug, derived from botanical extract, could treat aggressive breast cancer



March 23rd, 2006

A new clinical formulation extracted from a botanical may provide physicians with a new tool in treating aggressive late-stage breast cancer.

The oral anticancer drug BZL101, developed by Bionovo, Inc., is derived from the Asian botanical herba Scutellaria Barbata. Bionovo researchers believe the herb's main agent has the ability to specifically identify and target malignant cells, leaving normal cells intact and healthy.

BZL101 works by eliciting a cancer cell's innate mechanism of self-suicide, or apoptosis. The drug selectively releases Apoptosis Inducing Factor-1 (AIF1) from a cancer cell's mitochondrial membrane. AIF then moves to the cell's...


Source: Women's Health Weekly (2006-03-23)

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