Women's Health Weekly
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Breast Cancer
Breast cancer found associated with steroid receptor RNA activator protein expression
March 23rd, 2006
Breast cancer was associated with steroid receptor RNA activator (SRA) protein expression. "The SRA was originally described as the first functional non-coding RNA able to specifically coactivate the activity of steroid receptors. We previously demonstrated the existence in breast cancer cell lines of new SRA isoforms that, as opposed to the first cloned SRA RNA, encode for a 236-amino acid protein, SRAP," investigators in Canada reported. "To investigate the possible implications of the coding SRA RNA and SRAP expression on breast cancer progression, we examined by Western blot analysis 74 primary breast tumors of patients subsequently treated with...
Source: Women's Health Weekly (2006-03-23)
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