Women's Health Weekly
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Breast Cancer
Breast cancer treated with combination of oral vinorelbine and capecitabine
March 23rd, 2006
A combination of oral vinorelbine and capecitabine could be used to treat patients with metastatic breast cancer (MBC). "A phase I study was performed to determine the maximal tolerated dose, recommended doses (RDs), safety and efficacy of oral vinorelbine when combined with capecitabine in an all-oral chemotherapy regimen in patients with MBC, with pharmacokinetic blood sampling to investigate potential drug-drug interactions," scientists writing in the journal Annals of Oncology reported. "Forty-four patients with MBC received as first- or second-line chemotherapy, oral vinorelbine at a dose of 60 or 80 mg/m2 on days 1 and 8 (and...
Source: Women's Health Weekly (2006-03-23)
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