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Women's Health Weekly

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Cervical Cancer



Human papillomavirus tissue affinity may contribute to carcinogenic potential



March 23rd, 2006

Genetically distinct groups of human papillomavirus types may differ in tissue preferences with corresponding differences in carcinogenic potential.

"Approximately 15 human papillomavirus (HPV) types cause virtually all cervical cancer whereas other HPV types are unrelated to cancer," stated scientists at the U.S. National Institutes of Health. "We were interested in whether some noncarcinogenic types differ from carcinogenic in their affinity for the cervical transformation zone, where nearly all HPV-induced cancers occur."

P.E. Castle and colleagues explained, "To examine this possibility, we tested cervical specimens from 8,374 women without...


Source: Women's Health Weekly (2006-03-23)

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