Women's Health Weekly
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Breast Cancer
Research add new data to breast cancer body of knowledge
March 23rd, 2006
New findings from the United States and Ireland describe advances in breast cancer. Study 1: BRCA1 promoter methylation in sporadic breast cancer was associated with reduced gene copy number and chromosome 17 aneusomy. Investigators in the United States explained, "To explore the molecular mechanisms for the similarities between inherited and noninherited forms of breast cancer, we tested the hypothesis that inactivation of BRCA1 by promoter hypermethylation is associated with reduced gene copy number and chromosome 17 aneusomy as observed in tumors from BRCA1 mutation carriers. Using a combination of methylation-specific PCR analysis and...
Source: Women's Health Weekly (2006-03-23)
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