Women's Health Weekly
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Breast Cancer Vaccine
Breast cancer tumors frequently express cancer testis genes
March 23rd, 2006
Cancer testis genes are frequently expressed by primary breast cancer tumors. According to a study from Germany, "To determine the expression of cancer testis (CT) genes and antibody responses in a nonselected population of patients with primary breast cancer, we investigated the composite expression of 11 CT genes by RT-PCR in fresh biopsies of 100 consecutive cases of primary breast carcinoma and by immunohistology in selected RT-PCR-positive cases. Antibody responses against seven CT antigens were analyzed using recombinant antigen expression on yeast surface." "In 98 evaluable cases, SCP-1 and SSX-4 were expressed most frequently (both 65%),...
Source: Women's Health Weekly (2006-03-23)
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