Women's Health Weekly
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Cervical Cancer
Cervical cancer growth is inhibited by the angiogenesis modulator NOL7
March 23rd, 2006
Cervical cancer growth is inhibited by the angiogenesis modulator NOL7. "Cervical cancer is associated with human papilloma virus infection. However, this infection is insufficient to induce transformation and progression," scientists writing in the journal Oncogene report. "Loss of heterozygosity analyses suggest the presence of a tumor suppressor gene (TSG) on chromosome 6p21.3-p25. Here we report the cloning NOL7, its mapping to chromosome band 6p23, and localization of the protein to the nucleolus. Fluorescence in situ hybridization analysis demonstrated an allelic loss of an NOL7 in cultured tumor cells and human tumor samples," reported...
Source: Women's Health Weekly (2006-03-23)
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