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HIV/AIDS Drug Resistance

Infant-only prophylaxis eliminates nevirapine resistance development in mothers and infants

Published in Women's Health Weekly, March 23rd, 2006

Infant-only prophylaxis for HIV infection eliminates the development of nevirapine resistance in mothers and infants.

According to recent research from the United States, "We analyzed the development of nevirapine (NVP) resistance in human immunodeficiency virus type 1 (HIV-1)-infected Malawian infants who received regimens containing single dose NVP (SD-NVP) for the prevention of mother-to-child transmission (MTCT) of HIV-1.

"All infants received SD-NVP, and some randomly received zidovudine (ZDV) as well. Mothers did or did not receive SD-NVP on the basis of when they arrived at the hospital for delivery."

"In infants 6-8 weeks...

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