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Sexual & Reproductive Health

Androgen replacement focus of recent review

Published in Women's Health Weekly, April 6th, 2006

Androgen replacement should be reserved for women with severe deficiency due to an established cause.

According to a review from England, "Androgens in women either derive from direct ovarian production or from peripheral conversion of the adrenal sex steroid precursor, dehydroepiandrosterone, towards active androgens. Therefore, loss of adrenal or ovarian function, caused by Addison's disease or consequent to bilateral oophorectomy, results in severe androgen deficiency, clinically often associated with a loss of libido and energy."

"Importantly, physiological menopause does not necessarily lead to androgen deficiency, as androgen synthesis in the...

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