Genetics & Genomics
Gene expression profiling identifies molecular classifiers of ovarian cancer
Published in Women's Health Weekly, April 6th, 2006
"In order to elucidate the biological variance between normal ovarian surface epithelial (NOSE) and epithelial ovarian cancer (EOC) cells, and to build a molecular classifier to discover new markers distinguishing these cells, we analysed gene expression patterns of 65 primary cultures of these tissues by oligonucleotide microarray," wrote C. Lepage and colleagues, University of Montreal. "Unsupervised clustering highlights three subgroups of tumours: low malignant potential tumours, invasive...
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