Breast Cancer
Breast cancer resistance protein and p-glycoprotein modulated by corticosteroids
Published in Women's Health Weekly, April 17th, 2006
"Efflux transporters, p-glycoprotein and BCRP, located at barrier sites such as the blood-brain barrier may affect distribution of steroids used for treating chronic inflammatory conditions and thus the extent to which they may perturb the hypothalamic-pituitary-adrenal axis. In the present study, 6 different glucocorticoids were investigated for their possible interactions with these efflux transporters," investigators in England reported.
"Beclomethasone dipropionate, mometasone furoate and ciclesonide active principle but not...
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